Thyroid disease and children

Thyroid hormones play a very important role in healthy growth and development during childhood, impacting metabolism, the nervous system and organ functions.1 Therefore, it is vital that parents understand the signs and symptoms of thyroid disorders in children. It is also important to remember that treatments are available, and that early intervention will help to avoid any long-term issues or complications.1

Children diagnosed with thyroid problems need the support of their families to ensure they take their medication regularly and understand their condition. It is also recommended that schools or nurseries are informed so that they are aware of the child’s diagnosis and medication requirements.

Meet Hypo and Hyper, the Thyroid Butterflies

To spot the symptoms associated with hypothyroidism and hyperthyroidism, think of them as butterflies, each with a different personality: Hypo (short for hypothyroidism) and Hyper (short for hyperthyroidism).

Meet Hypo‒ the slow and sluggish butterfly

Hypo is a blue butterfly. He is slow moving compared with his friends and not growing as fast. He is often tired and sometimes sluggish. His skin is cold, and his heart rate is slower than that of other butterflies.

Meet Hyper ‒ the highly active and restless butterfly

Hyper is a thin, overly active and fidgety pink butterfly. She is irritable and easily upset. She is often hungry and eats a lot but still losing weight.

Could my baby experience thyroid problems?

Children can experience hypothyroidism from birth as they can be born without a properly working thyroid gland, a condition called congenital hypothyroidism.2 This condition can be difficult to spot at birth as babies may not have any symptoms or may only display mild symptoms that often go unrecognised.2

What should I look out for?

Typical symptoms of congenital hypothyroidism include:2,3

  • Prolonged jaundice
  • Excessive sleeping
  • Poor feeding
  • Poor muscle tone
  • Constipation
  • Cold hands and feet

To avoid the more serious effects of untreated congenital hypothyroidism – including impaired brain development – all newborns in Singapore gets their cord blood tested for congenital hypothyroidism.4 Babies who tested positive for high thyroid stimulating hormone (TSH) at birth will be called back for confirmatory testing and evaluation 3‒5 days afterbirth.3 Children with congenital hypothyroidism are treated with proper medication in the same way as adults.2 This treatment can ensure that the child continues to develop normally.2

If you are at all concerned that you or your child may be at risk for, or suffering from, thyroid problems, please discuss this with your doctor.

An underactive thyroid gland in children

The most common cause of acquired hypothyroidism in children is Hashimoto’s thyroiditis, where the body’s immune system attacks the thyroid gland and interferes with the production of thyroid hormones.6

The signs of hypothyroidism in children can vary depending on their age when the problem starts:

  • Babies may be jaundiced for longer than usual1
  • Older children may experience stunted growth in terms of their bones or teeth1
  • Children of school age may experience learning difficulties and puberty may be delayed1,5

Treatment

The goal of hypothyroidism treatment in children is to replace the missing thyroid hormone. The appropriate medication for hypothyroidism in adults is also recommended for use in children. However, the dose is tailored to match the specific weight and needs of the child.1

If you are at all concerned that you or your child may be at risk for, or suffering from, thyroid problems, please discuss this with your doctor. To assist you during your consultation, download our Wellbeing Diary to help you track the symptoms you or your child are experiencing.

An overactive thyroid gland in children

The autoimmune disorder Graves’ disease is responsible for almost all the cases of hyperthyroidism in children. Graves’ disease tends to be more common in teenagers than toddlers, and generally affects more girls than boys.1

Graves’ disease in children can often be difficult to identify because it develops slowly. However, there are common signs and symptoms to be aware of. These include:1

  • Changes in behaviour and school performance
  • Sleeplessness or restlessness
  • Irritability
  • Needing to get up in the night to urinate
  • An enlarged thyroid gland
  • Trembling hands
  • Slight bulging of the eyes
  • An increased appetite but combined with weight loss
  • Fast heart rate
  • Nervousness
  • Diarrhoea

Treatment

The goal of treatment in children with hyperthyroidism is to reduce the amount of thyroid hormone present in the bloodstream. There are several treatment options available, and treatment should be carefully discussed with a doctor. In children who experience side effects from anti-thyroid medications, surgery may be the preferred option.1 Radioactive iodine therapy is less likely to be used as the long-term effects in children and teenagers are not known.

If you are at all concerned that you or your child may be at risk for, or suffering from, thyroid problems, please discuss this with your doctor. To assist you during your consultation, download our Wellbeing Diary to help you track the symptoms you or your child are experiencing.

Summary

  • Thyroid hormones play a very important role in healthy growth and development during childhood
  • The symptoms and signs of thyroid disorders in children and adolescents may very depending on the age when the problem starts
  • Treatments for thyroid disease are available and early intervention will help to avoid any longer term issues or complications

References

SG-NONT-00025

Date of preparation: December 2023